Molecule Research Project

Myoglobin

1. Go to the NCBI , National Center for Biotechnology Information

http://www.ncbi.nlm.nih.gov/

2. To download a free molecular viewer for your computer go to

http://www.ncbi.nlm.nih.gov/Structure/CN3D/cn3dwin.shtml

Follow the directions for the installer

3.   Click on top menu – Structure

3. Search for Myoglobin – Click on first choice and open

What animal is used for this study.  Click on its name

Physeter catodon – Why is this organism a good model for the study of myoglobin?

Return to the previous page

4. Click on PDB .

Click on sequence details

What is the molecular mass of myoglobin?

How many amino acids are in myoglobin?

How many alpha helices?

What is the sequence of the AA?  Print out the sequence. Of download it to your computer.

    Return to previous page

     4.  Click on view 3-D structure

      Choose Open

      Look in upper menu - Styles

      Select rendering short cuts –

·         Worms

·         Tubes

·         Ball and stick

·         Space fill

·         Wires

SAVE TWO OF THESE AND PRINT . COMPARE.

      Select coloring short cuts

• Hydrophobicity
• Charge
• Domain
• Secondary structure

Grab Molecule and Rotate in Space