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Circulatory System

 

Materials once taken into the body must be transported to body tissues.

 

·        Some of these materials include

·        Gasses (CO2 & O2)

·        Nutrients

·        Hormones

·        This is done via the circulatory system.

 

Blood

·        Is a liquid tissue

·        Is composed of approx. 55% Plasma

·        Liquid component of blood

·        Contains salts, dissolved nutrients

·        Other 45% composed of 3 types of cells

·        Red blood cells

·        ~5 million RBC'c per cc of blood

·        Contains hemoglobin which carries O2 to cells, also carries CO2 away from cells

·        Each red blood cell can carry 1 billion molecules of O2

·        Live approx. 120 days, and are made in bone marrow at a rate of ~2 million/second

 

Red Blood Cells

 

·        White Blood Cells

·        Defend the cell from infection

·        Can engulf bacteria, and produce antibodies to fight viruses

·        Can move through body tissues

·        Are the target cells of HIV.

·        4000-11000 per cc of blood

 

White Blood Cell

 

·        Platelets

·        Are actually fragments of cells

·        Act as "plugs" to form clots surrounding breaks in the blood vessels

 

Blood Types:

·        Determined by presence or absence of certain proteins in blood.

·        These are A, B, O (absence of A or B) and Rh (+,-).

·        Your body defenses will attack any protein which it does not have.

·        Since AB+ have all the proteins, they can accept all blood types, but can only donate to other AB+ persons.  They are Universal Recipients.

·        Since O- have no proteins, they can Only receive blood from O- persons, but can donate blood to anyone.  They are Universal Donors.

 

Note: You cannot contract HIV or other blood-borne illnesses through donating blood.


 

Blood Vessels:

 

Blood is transported throughout the body via blood vessels - There are many types.

Classified according to if they carry blood to or away from the heart.

 

Away:

·        Arteries

·        Largest blood vessels.

·        Very elastic & thick-Surrounded by layers of smooth muscle.

·        Generally lead away from heart & carry oxygenated blood.

·        Lead into Arterioles

·        Arterioles

·        Smaller and thinner than arteries

·        Still lead away from heart

·        Lead to capillaries

·        Capillaries

·        Small thin vessels - usually only 1 RBC wide

·        Pass next to or near every cell in the body

·        Gas (CO2 & O2) & nutrient exchange occur here.

 

Blood Vessel comparison


Towards Heart

 

·        Venules

·        Thin walled vessels collect deoxygenated blood from capillaries.

·        Not as elastic as arteries, have little muscle surrounding

·        Pass blood into veins

·        Veins

·        Collect blood from venules

·        Thin walled, contain valves which only allow blood to go one way.

·        Skeletal muscle "squeeze" the veins to move blood back to the heart.

 

 

Veinous valves


 



Circulatory Pathways of Animals:

 

·        Animals have various types of circulatory systems:

·        2 General categories

o       Open circulatory system

§        Usually involves a fluid coined hemolymph

§        Involves blood leaving the vessels to directly contact individual cells.

o       Closed circulatory system

§        Blood never leaves vessel structures.

§        Is the vertebrate system.

 

open vs. closed circulatory systems


 

·        Closed circulatory systems have 3 general schemes, each being increasingly efficient.

 

o       Fish have a 2 chambered system where blood must pass through 2 capillary beds before returning to the heart. 

§        Lowers blood pressure

o       Reptiles have a 3 chambered system which increases blood flow/pressure since blood must pass through only 1 capillary bed per cycle.

§        Disadvantage: mixes oxygenated & deoxygenated blood

o       Mammals have a more efficient system with a 4 chambered heart.  Blood pressure is increased and there is no mixing of blood.

 



Human Circulation

 


 

The Cardiac cycle:

·        Vocab.

o       Systole = contraction phase

o       Diastole = relaxation phase

 

1.      Contraction impulse originates from sinoatrial (SA) node (aka. Pacemaker)

2.     Induces systole of atria which empty contents into ventricles.

3.     Atrioventricular (AV) node delays impulse ~0.1 second.

4.     Impulse is carried to the base of ventricles stimulating their contraction

 

 

 


 

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Mr. Stanley

Last updated: March 11, 2004